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"...as our knowledge of, and ability to measure, the biomechanics of the cornea improves, then so will there be the need for changes in the way we calculate intraocular pressure..."
(Translated from one of Hans Goldmann's original papers (ca. 1950, in German).
"We found that the Goldmann measurements weren't significantly different between contralateral eyes in any given patient. In contrast, the PASCAL DCT showed a higher pressure in the eye with greater damage. The only way we would have noticed a pressure difference is with the PASCAL".
Corneal Thickness is not the main culprit for errors in Applanation Tonometry: "In Refractive Surgery, the Goldman Error is likely due to a fundamental change in biomechanical properties [of the cornea], rather than a simple change in thickness."
Cynthia Roberts is Torrence A. Makley Research Professor (Department of Ophthalmology); Associate Professor of Biomedical Engineering, Ophthalmology, and Surgery, and Associate Director at the Biomedical Engineering Center at the Ohio State University, Columbus, OH. One of her main interests is in structural dynamics of the cornea.
"... We are (...) studying the fact that (applanation) IOP measurements probably do not reveal true IOP for reasons related to corneal structure and function. Although a hot topic, corneal thickness is probably not as important as the cornea’s elastic response to being indented..." Link to Full Text.
H. Quigley is Director of the Glaucoma Service and of the Dana Center for Preventive Ophthalmology at the Wilmer Institute, Johns Hopkins University, Baltimore, and a founding member of the American Glaucoma Society.
"Based (…) on our initial experience with the commercial PASCAL device, DCT appears to be a promising new technology that is highly accurate, easy to use, and independent of corneal thickness and edema. (…). Its use would appear to be particularly warranted for IOP measurement in post-LASIK patients and other patients whose corneas are thinner or thicker than average and who can no longer achieve accurate readings by force tonometry."
Robert L. Stamper MD, Professor of Clinical Ophthalmology (University of California, San Francisco, CA; USA) (from "Dynamic Contour Tonometry. Overcoming the limitations of applanation tonometry”; R.L. Stamper, Glaucoma Today, April 2004).
"Intraocular pressure measurements obtained by dynamic contour tonometry in African Americans were less influenced by corneal properties than measurements obtained using Goldmann applanation tonometry. "
Robert N. Weinreb MD, is Director of the Hamilton Glaucoma Center, and Distinguished Professor and Vice Chair, Department of Ophthalmology, University of California, San Diego, La Jolla,, CA; USA). Felipe Medeiros, MD, PhD, is Assistant Clinical Professor in the UCSD Department of Ophthalmology. Pamela Sample, PhD, is Professor of Ophthalmology at the Shiley Eye Center of UCSD and Director of Clinical Vision research at the Hamilton Glaucoma Center. (Ophthalmology 114 [4], 658, 2007).
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My technicians and I find the slitlamp-mounted PASCAL in my office to be easy to use, quite consistent, and a giant leap forward in IOP measurements.
Jay McDonald II of McDonald Eye Associates (Fayetteville, Arkansas, USA) is Assistant Clinical Professor of Ophthalmology at the University of Arkansas School of Medicine, and President of the American College of Eye Surgeons (ACES). (statement made in August 2006)
"Adjusting Goldmann tonometry measurements by using patients central corneal thickness (CCT) is a fallacious attempt to add precision to a very noisy measurement." … "New technologies, such as […] the PASCAL Dynamic Contour Tonometer, which takes tonometry measurements that are less affected by CCT, represent the next generation of glaucoma testing."
(quoted from Ocular Surgery News, Europe/Asia-Pacific Edition Vol. 17, No. 11, November 2006, page 8; a report on Dr. Brandt's keynote lecture presented at the OSN Symposium in New York.) James D. Brandt, MD, is Professor of Ophthalmology and Director of the Glaucoma Service at UC Davis in Sacramento, California.
"Dynamic Contour Tonometry appears to be less affected by corneal thickness than Goldmann or Tonopen applanation tonometry. Increased OPA appears to correlate with smaller cup-to-disc ratios and increased corneal thickness. Measuring OPA using the dynamic contour tonometer may be useful in assessing severity of glaucoma."
Leon Herndon is Assistant Professor of Ophthalmology at the Duke Medical Center, Durham NC (statement made in October 2005).
"In my opinion the PASCAL DCT is substantially more important than pachymetry and correction tables”
Thomas Neuhann,MD, is Professor of Ophthalmology in the MEdical Faculty of the Technical University of Munich, germany, and Director of of the ALZ Eye Clinic in Munich.
"I have been using the PASCAL Dynamic Contour Tonometer for the past three years. The PASCAL is an indispensible part of my office management of glaucoma patients. In complex cases of ocular hypertensives and glaucoma suspects, the PASCAL reading often tips my hand one way or the other in whether or not to recommed treatment."
Lawrence Stone, MD is a glaucoma specialist at the Stone Eye Center in Chicago, Ill. (statement made in January 2007)
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